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Invitrogen
PPAN Polyclonal Antibody
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Product Details
PA5-106430
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PPAN(Accession Q9NQ55), corresponding to amino acid residues Q408-D458.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PPAN.
Target Information
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brix domain-containing protein 3; homolog of S. cerevisiae SSF1; Peter Pan homolog; second-step splicing factor 1; Ssf-1; suppressor of sterile four 1; Suppressor of SWI4 1 homolog
Gene Aliases: A230087P06Rik; BXDC3; PPAN; SSF; SSF-1; SSF1; SSF2
UniProt ID: (Human) Q9NQ55, (Mouse) Q91YU8
Entrez Gene ID: (Human) 56342, (Rat) 298699, (Mouse) 235036
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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