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|Tested species reactivity||Human, Mouse, Sheep, Pig, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide surrounding amino acid 25 of human PPARa.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol, 1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||3-6 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
PA1-32484 detects PPAR alpha from human, mouse, rat, pig and sheep samples.
PA1-32484 has been successfully used in Western blot applications. Detects a band of approximately 52 kDa.
The PA1-32484 immunogen is: Synthetic peptide surrounding amino acid 25 of human PPARa.
Peroxisome proliferators are non-genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family, termed peroxisome proliferator activated receptors (PPARs). Nuclear h
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Overexpression of peroxisome proliferator-activated receptor α in pancreatic β-cells improves glucose tolerance in diet-induced obese mice.
PA1-32484 was used in immunohistochemistry to study the effect of pancreatic-beta cell overexpression of PPARalpha on glucose-tolerance in a murine model of diet-induced obesity
|Hogh KL,Uy CE,Asadi A,Baker RK,Riedel MJ,Gray SL||Experimental physiology (98:564)||2013|
nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor, alpha; Peroxisome Proliferator Activated Receptor Alpha; peroxisome proliferator-activated nuclear receptor alpha variant 3; peroxisome proliferator-activated receptor alpha; PPAR-alpha
4933429D07Rik; AW742785; hPPAR; NR1C1; PPAR; PPAR-alpha; PPARA; PPARALPHA