Product References
Yin-Chen-Hao Tang Attenuates Severe Acute Pancreatitis in Rat: An Experimental Verification of In silico Network Target Prediction.
Frontiers in pharmacology
Xiang H,Wang G,Qu J,Xia S,Tao X,Qi B,Zhang Q,Shang D
Thu Oct 01 00:00:00 EDT 2020
Renoprotective Effect of Danhong Injection on Streptozotocin-Induced Diabetic Rats through a Peroxisome Proliferator-Activated Receptor γ Mediated Pathway.
Evidence-based complementary and alternative medicine : eCAM
Yang X,Xiao X,Wang H,Li Y,Wang L,Li G,Deng S
Thu Oct 01 00:00:00 EDT 2020
Fluid Retention Caused by Rosiglitazone Is Related to Increases in AQP2 and αENaC Membrane Expression.
PPAR research
Xu J,Pan M,Wang X,Xu L,Li L,Xu C
Thu Oct 01 00:00:00 EDT 2020
Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis.
Frontiers in molecular neuroscience
Zhao Z,Zhang L,Guo XD,Cao LL,Xue TF,Zhao XJ,Yang DD,Yang J,Ji J,Huang JY,Sun XL
Wed Sep 30 00:00:00 EDT 2020
Dan-Lou Prescription Inhibits Foam Cell Formation Induced by ox-LDL via the TLR4/NF-κB and PPARγ Signaling Pathways.
Frontiers in physiology
Gao LN,Zhou X,Lu YR,Li K,Gao S,Yu CQ,Cui YL
Wed Sep 30 00:00:00 EDT 2020
Kisspeptin Receptor GPR54 Promotes Adipocyte Differentiation and Fat Accumulation in Mice.
Frontiers in physiology
Wang T,Cui X,Xie L,Xing R,You P,Zhao Y,Yang Y,Xu Y,Zeng L,Chen H,Liu M
Wed Sep 30 00:00:00 EDT 2020
Mesenchymal glioblastoma constitutes a major ceRNA signature in the TGF-β pathway.
Theranostics
Wang Q,Cai J,Fang C,Yang C,Zhou J,Tan Y,Wang Y,Li Y,Meng X,Zhao K,Yi K,Zhang S,Zhang J,Jiang C,Zhang J,Kang C
Fri Sep 06 00:00:00 EDT 2019
Taurine improves low-level inorganic arsenic-induced insulin resistance by activating PPARγ-mTORC2 signalling and inhibiting hepatic autophagy.
Journal of cellular physiology
Gao N,Yao X,Jiang L,Yang L,Qiu T,Wang Z,Pei P,Yang G,Liu X,Sun X
Mon Apr 01 00:00:00 EDT 2019
Preparation and protective effects of 1,8-cineole-loaded self-microemulsifying drug delivery system on lipopolysaccharide-induced endothelial injury in mice.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Jiang F,Wu G,Li W,Yang J,Yan J,Wang Y,Yao W,Zhou X,He Z,Wu L,Xiao C,Xiao T,Zhang M,Shen X,Tao L
Tue Jan 15 00:00:00 EST 2019
EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang J,Qiu H,Huang J,Ding S,Huang B,Zhou P,Jiang Q
Tue Jan 01 00:00:00 EST 2019
Taurine rescues the arsenic-induced injury in the pancreas of rat offsprings and in the INS-1 cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Q,Bai J,Yao X,Jiang L,Wu W,Yang L,Gao N,Qiu T,Yang G,Habtemariam Hidru T,Sun X
Tue Jan 01 00:00:00 EST 2019
Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells.
Life sciences
Xu L,Liu JT,Li K,Wang SY,Xu S
Tue Jan 01 00:00:00 EST 2019
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
EBioMedicine
Lyu Z,Mao Z,Li Q,Xia Y,Liu Y,He Q,Wang Y,Zhao H,Lu Z,Zhou Q
Sat Dec 01 00:00:00 EST 2018
PPARγ maintains the metabolic heterogeneity and homeostasis of renal tubules.
EBioMedicine
Lyu Z,Mao Z,Li Q,Xia Y,Liu Y,He Q,Wang Y,Zhao H,Lu Z,Zhou Q
Sat Dec 01 00:00:00 EST 2018
PPAR-γ Agonist Alleviates Liver and Spleen Pathology via Inducing Treg Cells during Schistosoma japonicum Infection.
Journal of immunology research
Zhu Y,Ni Y,Liu R,Hou M,Yang B,Song J,Sun H,Xu Z,Ji M
Mon Nov 05 00:00:00 EST 2018
Enhanced anti-obesity effects of bacterial cellulose combined with konjac glucomannan in high-fat diet-fed C57BL/6J mice.
Food & function
Zhai X,Lin D,Zhao Y,Li W,Yang X
Wed Oct 17 00:00:00 EDT 2018
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Journal of cellular and molecular medicine
Qin DD,Yang YF,Pu ZQ,Liu D,Yu C,Gao P,Chen JC,Zong C,Zhang YC,Li X,Wang XD,Liu YT
Mon Oct 01 00:00:00 EDT 2018
NR4A1 retards adipocyte differentiation or maturation via enhancing GATA2 and p53 expression.
Journal of cellular and molecular medicine
Qin DD,Yang YF,Pu ZQ,Liu D,Yu C,Gao P,Chen JC,Zong C,Zhang YC,Li X,Wang XD,Liu YT
Mon Oct 01 00:00:00 EDT 2018
Bexarotene protects against neurotoxicity partially through a PPARγ-dependent mechanism in mice following traumatic brain injury.
Neurobiology of disease
He J,Liu H,Zhong J,Guo Z,Wu J,Zhang H,Huang Z,Jiang L,Li H,Zhang Z,Liu L,Wu Y,Qi L,Sun X,Cheng C
Sat Sep 01 00:00:00 EDT 2018
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Oxidative medicine and cellular longevity
Sun HJ,Chen D,Wang PY,Wan MY,Zhang CX,Zhang ZX,Lin W,Zhang F
Fri Aug 17 00:00:00 EDT 2018
Corilagin Counteracts IL-13Rα1 Signaling Pathway in Macrophages to Mitigate Schistosome Egg-Induced Hepatic Fibrosis.
Frontiers in cellular and infection microbiology
Li YQ,Chen YF,Dang YP,Wang Y,Shang ZZ,Ma Q,Wang YJ,Zhang J,Luo L,Li QQ,Zhao L
Mon Jul 09 00:00:00 EDT 2018
Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice.
Biochemical and biophysical research communications
Zhang J,Qiu H,Huang J,Ding S,Huang B,Wu Q,Jiang Q
Sat Jul 07 00:00:00 EDT 2018
Network pharmacology-based strategy for predicting active ingredients and potential targets of Yangxinshi tablet for treating heart failure.
Journal of ethnopharmacology
Chen L,Cao Y,Zhang H,Lv D,Zhao Y,Liu Y,Ye G,Chai Y
Tue Jun 12 00:00:00 EDT 2018
Nesfatin-1 promotes VSMC migration and neointimal hyperplasia by upregulating matrix metalloproteinases and downregulating PPARγ.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang JR,Lu QB,Feng WB,Wang HP,Tang ZH,Cheng H,Du Q,Wang YB,Li KX,Sun HJ
Fri Jun 01 00:00:00 EDT 2018
Rosiglitazone Inhibits Angiotensin II-Induced Proliferation of Glomerular Mesangial Cells via the Gαq/Plcβ4/TRPC Signaling Pathway.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Wei L,Mao J,Lu J,Gao J,Zhu D,Tian L,Chen Z,Jia L,Wang L,Fu R
Mon Mar 12 00:00:00 EDT 2018
Egr-1 mediates leptin-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Molecular biology of the cell
Xie X,Li S,Zhu Y,Liu L,Ke R,Wang J,Yan X,Yang L,Gao L,Zang W,Li M
Thu Feb 01 00:00:00 EST 2018
Activation of peroxisome proliferation-activated receptor-γ inhibits transforming growth factor-β1-induced airway smooth muscle cell proliferation by suppressing Smad-miR-21 signaling.
Journal of cellular physiology
Liu L,Pan Y,Zhai C,Zhu Y,Ke R,Shi W,Wang J,Yan X,Su X,Song Y,Gao L,Li M
Mon Jan 01 00:00:00 EST 2018
Flavonoid-enriched extract from Hippophae rhamnoides seed reduces high fat diet induced obesity, hypertriglyceridemia, and hepatic triglyceride accumulation in C57BL/6 mice.
Pharmaceutical biology
Yang X,Wang Q,Pang ZR,Pan MR,Zhang W
Fri Dec 01 00:00:00 EST 2017
Activation of PPARγ inhibits HDAC1-mediated pulmonary arterial smooth muscle cell proliferation and its potential mechanisms.
European journal of pharmacology
Li F,Zhu Y,Wan Y,Xie X,Ke R,Zhai C,Pan Y,Yan X,Wang J,Shi W,Li M
Sun Nov 05 00:00:00 EDT 2017
The novel ZIP4 regulation and its role in ovarian cancer.
Oncotarget
Fan Q,Cai Q,Li P,Wang W,Wang J,Gerry E,Wang TL,Shih IM,Nephew KP,Xu Y
Fri Oct 27 00:00:00 EDT 2017
The novel ZIP4 regulation and its role in ovarian cancer.
Oncotarget
Fan Q,Cai Q,Li P,Wang W,Wang J,Gerry E,Wang TL,Shih IM,Nephew KP,Xu Y
Fri Oct 27 00:00:00 EDT 2017
5-HT induces PPAR γ reduction and proliferation of pulmonary artery smooth muscle cells via modulating GSK-3β/β-catenin pathway.
Oncotarget
Ke R,Xie X,Li S,Pan Y,Wang J,Yan X,Zang W,Gao L,Li M
Fri Sep 22 00:00:00 EDT 2017
miR-148a-3p regulates adipocyte and osteoblast differentiation by targeting lysine-specific demethylase 6b.
Gene
Tian L,Zheng F,Li Z,Wang H,Yuan H,Zhang X,Ma Z,Li X,Gao X,Wang B
Tue Sep 05 00:00:00 EDT 2017
MicroRNA-27a/b mediates endothelin-1-induced PPARγ reduction and proliferation of pulmonary artery smooth muscle cells.
Cell and tissue research
Xie X,Li S,Zhu Y,Liu L,Pan Y,Wang J,Shi W,Song Y,Yang L,Gao L,Zang W,Li M
Fri Sep 01 00:00:00 EDT 2017
Activation of Adiponectin Receptor Regulates Proprotein Convertase Subtilisin/Kexin Type 9 Expression and Inhibits Lesions in ApoE-Deficient Mice.
Arteriosclerosis, thrombosis, and vascular biology
Sun L,Yang X,Li Q,Zeng P,Liu Y,Liu L,Chen Y,Yu M,Ma C,Li X,Li Y,Zhang R,Zhu Y,Miao QR,Han J,Duan Y
Sat Jul 01 00:00:00 EDT 2017
The stress-response molecule NR4A1 resists ROS-induced pancreatic β-cells apoptosis via WT1.
Cellular signalling
Zong C,Qin D,Yu C,Gao P,Chen J,Lu S,Zhang Y,Liu Y,Yang Y,Pu Z,Li X,Fu Y,Guan Q,Wang X
Sat Jul 01 00:00:00 EDT 2017
Pentamethylquercetin induces adipose browning and exerts beneficial effects in 3T3-L1 adipocytes and high-fat diet-fed mice.
Scientific reports
Han Y,Wu JZ,Shen JZ,Chen L,He T,Jin MW,Liu H
Tue Apr 25 00:00:00 EDT 2017
PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a.
Neuropharmacology
Ji J,Zeng XN,Cao LL,Zhang L,Zhao Z,Yang DD,Sun XL
Wed Feb 01 00:00:00 EST 2017
Di-(2-ethylhexyl) phthalate could disrupt the insulin signaling pathway in liver of SD rats and L02 cells via PPARγ.
Toxicology and applied pharmacology
Zhang W,Shen XY,Zhang WW,Chen H,Xu WP,Wei W
Wed Feb 01 00:00:00 EST 2017
Targeting EZH1 and EZH2 contributes to the suppression of fibrosis-associated genes by miR-214-3p in cardiac myofibroblasts.
Oncotarget
Zhu WS,Tang CM,Xiao Z,Zhu JN,Lin QX,Fu YH,Hu ZQ,Zhang Z,Yang M,Zheng XL,Wu SL,Shan ZX
Tue Nov 29 00:00:00 EST 2016
Dioscin attenuates gastric ischemia/reperfusion injury through the down-regulation of PKC/ERK1/2 signaling via PKCα and PKCβ2 inhibition.
Chemico-biological interactions
Hu Y,Tao X,Han X,Xu L,Yin L,Qi Y,Zhao Y,Xu Y,Wang C,Peng J
Tue Oct 25 00:00:00 EDT 2016
A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.
Molecular bioSystems
Chen L,Lv D,Wang D,Chen X,Zhu Z,Cao Y,Chai Y
Tue Oct 18 00:00:00 EDT 2016
Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen: A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ-DEPENDENT MECHANISM.
The Journal of biological chemistry
Yu M,Jiang M,Chen Y,Zhang S,Zhang W,Yang X,Li X,Li Y,Duan S,Han J,Duan Y
Fri Aug 12 00:00:00 EDT 2016
Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen: A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ-DEPENDENT MECHANISM.
The Journal of biological chemistry
Yu M,Jiang M,Chen Y,Zhang S,Zhang W,Yang X,Li X,Li Y,Duan S,Han J,Duan Y
Fri Aug 12 00:00:00 EDT 2016
Activation of Peroxisome Proliferator-activated Receptor γ (PPARγ) and CD36 Protein Expression: THE DUAL PATHOPHYSIOLOGICAL ROLES OF PROGESTERONE.
The Journal of biological chemistry
Yang X,Zhang W,Chen Y,Li Y,Sun L,Liu Y,Liu M,Yu M,Li X,Han J,Duan Y
Fri Jul 15 00:00:00 EDT 2016
Taurine protects against As2O3-induced autophagy in livers of rat offsprings through PPARγ pathway.
Scientific reports
Bai J,Yao X,Jiang L,Zhang Q,Guan H,Liu S,Wu W,Qiu T,Gao N,Yang L,Yang G,Sun X
Mon Jun 13 00:00:00 EDT 2016
MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling.
Biochemical and biophysical research communications
Jin M,Wu Y,Wang J,Chen J,Huang Y,Rao J,Feng C
Fri May 20 00:00:00 EDT 2016
Naringin ameliorates cognitive deficits in streptozotocin-induced diabetic rats.
Iranian journal of basic medical sciences
Liu X,Liu M,Mo Y,Peng H,Gong J,Li Z,Chen J,Xie J
Fri Apr 01 00:00:00 EDT 2016
Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cells.
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology
Ma X,Li SF,Qin ZS,Ye J,Zhao ZL,Fang HH,Yao ZW,Gu MN,Hu YW
Thu Mar 03 00:00:00 EST 2016
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signaling.
Scientific reports
Zhang X,Chang A,Li Y,Gao Y,Wang H,Ma Z,Li X,Wang B
Fri Dec 11 00:00:00 EST 2015
Elevation of miR-27b by HPV16 E7 inhibits PPARγ expression and promotes proliferation and invasion in cervical carcinoma cells.
International journal of oncology
Zhang S,Liu F,Mao X,Huang J,Yang J,Yin X,Wu L,Zheng L,Wang Q
Sun Nov 01 00:00:00 EDT 2015
MicroRNA-130a and -130b enhance activation of hepatic stellate cells by suppressing PPARγ expression: A rat fibrosis model study.
Biochemical and biophysical research communications
Lu L,Wang J,Lu H,Zhang G,Liu Y,Wang J,Zhang Y,Shang H,Ji H,Chen X,Duan Y,Li Y
Fri Sep 25 00:00:00 EDT 2015
Systemic adaptation of lipid metabolism in response to low- and high-fat diet in Nile tilapia (Oreochromis niloticus).
Physiological reports
He AY,Ning LJ,Chen LQ,Chen YL,Xing Q,Li JM,Qiao F,Li DL,Zhang ML,Du ZY
Sat Aug 01 00:00:00 EDT 2015
miR-20a regulates adipocyte differentiation by targeting lysine-specific demethylase 6b and transforming growth factor-β signaling.
International journal of obesity (2005)
Zhou J,Guo F,Wang G,Wang J,Zheng F,Guan X,Chang A,Zhang X,Dai C,Li S,Li X,Wang B
Sat Aug 01 00:00:00 EDT 2015
miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.
Scientific reports
Chen K,He H,Xie Y,Zhao L,Zhao S,Wan X,Yang W,Mo Z
Tue Jul 07 00:00:00 EDT 2015
Administration of Danhong Injection to diabetic db/db mice inhibits the development of diabetic retinopathy and nephropathy.
Scientific reports
Liu M,Pan Q,Chen Y,Yang X,Zhao B,Jia L,Zhu Y,Zhang B,Gao X,Li X,Han J,Duan Y
Wed Jun 10 00:00:00 EDT 2015
Human cytomegalovirus infection interferes with the maintenance and differentiation of trophoblast progenitor cells of the human placenta.
Journal of virology
Tabata T,Petitt M,Zydek M,Fang-Hoover J,Larocque N,Tsuge M,Gormley M,Kauvar LM,Pereira L
Fri May 01 00:00:00 EDT 2015
miR-223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR-223/FGFR2 Regulatory Feedback Loop.
Stem cells (Dayton, Ohio)
Guan X,Gao Y,Zhou J,Wang J,Zheng F,Guo F,Chang A,Li X,Wang B
Fri May 01 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.
Endocrine
Pan X,Wang P,Luo J,Wang Z,Song Y,Ye J,Hou X
Wed Apr 01 00:00:00 EDT 2015
Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.
Endocrine
Pan X,Wang P,Luo J,Wang Z,Song Y,Ye J,Hou X
Wed Apr 01 00:00:00 EDT 2015
Rhizoma Dioscoreae Nipponicae polysaccharides protect HUVECs from H2O2-induced injury by regulating PPARγ factor and the NADPH oxidase/ROS-NF-κB signal pathway.
Toxicology letters
Jin Y,Liu K,Peng J,Wang C,Kang L,Chang N,Sun H
Mon Jan 05 00:00:00 EST 2015
Nitro-oleic acid downregulates lipoprotein-associated phospholipase A2 expression via the p42/p44 MAPK and NFκB pathways.
Scientific reports
Wang G,Ji Y,Li Z,Han X,Guo N,Song Q,Quan L,Wang T,Han W,Pang D,Ouyang H,Tang X
Fri May 09 00:00:00 EDT 2014
PPARγ mediates the effects of WIN55,212-2, an synthetic cannabinoid, on the proliferation and apoptosis of the BEL-7402 hepatocarcinoma cells.
Molecular biology reports
Hong Y,Zhou Y,Wang Y,Xiao S,Liao DJ,Zhao Q
Fri Nov 01 00:00:00 EDT 2013
miR-30e reciprocally regulates the differentiation of adipocytes and osteoblasts by directly targeting low-density lipoprotein receptor-related protein 6.
Cell death & disease
Wang J,Guan X,Guo F,Zhou J,Chang A,Sun B,Cai Y,Ma Z,Dai C,Li X,Wang B
Thu Oct 10 00:00:00 EDT 2013
2, 3, 5, 4'-Tetrahydroxystilbene-2-O-beta-D-glucoside improves gastrointestinal motility disorders in STZ-induced diabetic mice.
PloS one
Chang MJ,Xiao JH,Wang Y,Yan YL,Yang J,Wang JL
Tue Jun 11 00:00:00 EDT 2013