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This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein, which is expressed specifically in photoreceptors and the pineal, has been suggested to play a role in the visual system. This gene shares high sequence similarity with the Drosophila retinal degeneration C gene.
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Protein Aliases: PPEF-2; protein phosphatase 7, catalytic subunit, beta isozyme; protein phosphatase with EF hands 2; protein phosphatase, EF hand calcium-binding domain 2; protein phosphatase, EF-hand calcium binding domain 2; Serine/threonine-protein phosphatase with EF-hands 2
Gene Aliases: PPEF2; PPP7CB
UniProt ID: (Human) O14830
Entrez Gene ID: (Human) 5470
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