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Invitrogen
PPFIA2 Polyclonal Antibody
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FIGURE: 1 / 2
PPFIA2 Antibody (PA5-31450) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of PPFIA2 was performed in DIV9 rat E18 primary cortical neuron cells fixed in 4% paraformaldehyde at RT for 15 min. Green: PPFIA2 Polyclonal Antibody (Product # PA5-31450) diluted at 1:500. Red: beta Tubulin 3/ Tuj1, stained by beta Tubulin 3/ Tuj1 antibody. Blue: Fluoroshield with DAPI.
Product Details
PA5-31450
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human Liprin alpha 2. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.98 mg/mL
Amount
98 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (85%), Rhesus Monkey (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein is most closely related to PPFIA1, a liprin family member known to interact with the protein phosphatase LAR. The expression of this gene is found to be downregulated by androgens in a prostate cancer cell line.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: liprin-alpha 2; Liprin-alpha-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2; protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; PTPRF interacting protein alpha 2; PTPRF-interacting protein alpha-2; unnamed protein product
Gene Aliases: 5330438O12; B230207K17Rik; E130120L08Rik; mKIAA4112; PPFIA2
UniProt ID: (Human) O75334, (Mouse) Q8BSS9
Entrez Gene ID: (Human) 8499, (Rat) 362876, (Mouse) 327814
cell-matrix adhesion
synapse organization
regulation of dendritic spine development
regulation of dendritic spine morphogenesis
presynapse organization
dense core granule cytoskeletal transport
maintenance of postsynaptic density structure
regulation of synaptic vesicle exocytosis
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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