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Fabgennix
Phospho-PKC eta (Ser28, Ser32) Polyclonal Antibody, Biotin
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Product Details
PPKCETA-140-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 1-50 on human PKC eta protein. Phosphorylated S28 & S32.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC26269; MGC5363; nPKC-eta; PKC-L; Protein kinase C eta type; protein kinase C-eta; Protein uPEP2; unnamed protein product
Gene Aliases: nPKC-eta; PKC-L; Pkch; PKCL; PRKCH; PRKCL; uORF2
UniProt ID: (Human) P24723, (Mouse) P23298, (Rat) Q64617
Entrez Gene ID: (Human) 5583, (Mouse) 18755, (Rat) 81749
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
calcium-independent protein kinase C activity
protein kinase inhibitor activity
protein binding
ATP binding
zinc ion binding
kinase activity
transferase activity
enzyme binding
protein serine/threonine kinase inhibitor activity
small GTPase binding
translation regulator activity
metal ion binding
protein serine kinase activity
protein serine/threonine kinase binding
transferase activity, transferring phosphorus-containing groups
Ral GTPase binding
non-receptor serine/threonine protein kinase
regulation of translation
protein phosphorylation
signal transduction
positive regulation of macrophage derived foam cell differentiation
negative regulation of translation
cell differentiation
positive regulation of translation in response to stress
cellular response to amino acid starvation
negative regulation of glial cell apoptotic process
intracellular signal transduction
positive regulation of keratinocyte differentiation
positive regulation of B cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
positive regulation of glial cell proliferation
phospholipase C/protein kinase C signal transduction
positive regulation of protein localization to plasma membrane
regulation of bicellular tight junction assembly
phosphorylation
protein kinase C signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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