Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 9
Recommended positive controls: Raji, mouse brain, PC-12, Rat2.
Predicted reactivity: Mouse (98%), Rat (99%), Xenopus laevis (87%), Rabbit (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PPM1A (Protein phosphatase 1A) is also named as PPPM1A and belongs to the PP2C family. It is a serine/threonine protein phosphatase that is essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and that it negatively controls many signaling pathways which are critical for trophoblast invasion. This protein distributes in both the cytoplasm and nucleus of mammalian cells. It has 2 isoforms produced by alternative splicing.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IA; Mpp alpha; PP2C-alpha; Protein phosphatase 1A; protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform; protein phosphatase 1A, magnesium dependent, alpha isoform; Protein phosphatase 2C isoform alpha; Protein phosphatase IA; Protein phosphatase type 1A (formely 2C) Mg-dependent alpha isoform; Protein phosphatase type 1A (formely 2C), Mg-dependent, alpha isoform; protein phosphatase, Mg2+/Mn2+ dependent, 1A
Gene Aliases: 2310003C21Rik; 2900017D14Rik; AI427932; AU017636; MMPa-2; MPPa-1; PP2C-ALPHA; Pp2c1; PP2CA; PP2Calpha; PPM1A; PPPM1A
UniProt ID: (Human) P35813, (Mouse) P49443, (Rat) P20650
Entrez Gene ID: (Human) 5494, (Mouse) 19042, (Rat) 24666
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support