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PPM1D Polyclonal Antibody
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FIGURE: 1 / 1
PPM1D Antibody (600-401-DS3) in WB
Western Blot of Rabbit anti-PPM1D antibody. Lane A: 3T3 cell lysate. Primary antibody: PPM1D antibody at 1 µg/mL overnight at 4°C. Secondary antibody: Goat anti-Rabbit HRP secondary antibody. Block: 5% BLOTTO. Predicted/Observed size: 67 kDa, 68 kDa for PPM1D.
Product Details
600-401-DS3
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-PPM1D antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid peptide near the C-terminus of human PPM1D.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: p53-induced protein phosphatase 1; PP2C delta; PP2C-delta; PP2CD; Protein phosphatase 1D; protein phosphatase 1D magnesium-dependent, delta isoform; Protein phosphatase 2C isoform delta; Protein phosphatase magnesium-dependent 1 delta; protein phosphatase Wip1; unnamed protein product; wild-type p53-induced phosphatase 1; WIP 1
Gene Aliases: AV338790; IDDGIP; JDVS; PP2C-DELTA; PPM1D; WIP1
UniProt ID: (Human) O15297, (Mouse) Q9QZ67
Entrez Gene ID: (Human) 8493, (Rat) 287585, (Mouse) 53892
protein serine/threonine kinase activity
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein binding
hydrolase activity
cation binding
metal ion binding
mitogen-activated protein kinase binding
molecular_function
catalytic activity
magnesium-dependent protein serine/threonine phosphatase activity
G2/M transition of mitotic cell cycle
cellular response to starvation
response to bacterium
peptidyl-threonine dephosphorylation
methylation-dependent chromatin silencing
protein dephosphorylation
negative regulation of cell proliferation
response to radiation
DNA damage response, signal transduction by p53 class mediator
negative regulation of gene expression, epigenetic
regulation of transcription initiation from RNA polymerase II promoter
regulation of intracellular signal transduction
cell cycle
dephosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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