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Bioss
PPM1D Polyclonal Antibody
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Product Details
BS-2447R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human PPM1D, amino acids 201-300.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a type IV membrane protein. It is present in the plasma membrane and intracellular vesicles. It may also be associated with the cytoskeleton. This protein may function in vesicle trafficking, membrane fusion, protein complex assembly and cell motility. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: p53-induced protein phosphatase 1; PP2C delta; PP2C-delta; PP2CD; Protein phosphatase 1D; protein phosphatase 1D magnesium-dependent, delta isoform; Protein phosphatase 2C isoform delta; Protein phosphatase magnesium-dependent 1 delta; protein phosphatase Wip1; unnamed protein product; wild-type p53-induced phosphatase 1; WIP 1
Gene Aliases: AV338790; IDDGIP; JDVS; PP2C-DELTA; PPM1D; WIP1
UniProt ID: (Human) O15297, (Mouse) Q9QZ67
Entrez Gene ID: (Human) 8493, (Rat) 287585, (Mouse) 53892
protein serine/threonine kinase activity
phosphoprotein phosphatase activity
protein serine/threonine phosphatase activity
protein binding
hydrolase activity
cation binding
metal ion binding
mitogen-activated protein kinase binding
molecular_function
catalytic activity
magnesium-dependent protein serine/threonine phosphatase activity
G2/M transition of mitotic cell cycle
cellular response to starvation
response to bacterium
peptidyl-threonine dephosphorylation
methylation-dependent chromatin silencing
protein dephosphorylation
negative regulation of cell proliferation
response to radiation
DNA damage response, signal transduction by p53 class mediator
negative regulation of gene expression, epigenetic
regulation of transcription initiation from RNA polymerase II promoter
regulation of intracellular signal transduction
cell cycle
dephosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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