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          • Primary Antibodies ›
          • PPM1E Antibodies

          Proteintech

          PPM1E Polyclonal Antibody

          View all (12) PPM1E antibodies

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          Cite PPM1E Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          PPM1E Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          PPM1E Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          PPM1E Antibody (25089-1-AP) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using PPM1E antibody (25089-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG (H+L), CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          PPM1E Antibody in Immunocytochemistry (ICC/IF)
          PPM1E Antibody in Immunocytochemistry (ICC/IF)
          PPM1E Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PPM1E Antibody in Western Blot (WB)
          PPM1E Polyclonal Antibody

          Product Details

          25089-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:5,000-1:50,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:200-1:800
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          PPM1E fusion protein Ag18751
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.9 mg/mL

          Amount

          135 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice

          Product Specific Information

          Immunogen sequence: EESDWTENSF QGGQEDGGDD KENHGECKRP WPQHQCSAPA DLGYDGRVDS FTDRTSLSPG SQINVLEDPG YLDLTQIEAS KPHSAQFLLP VEMFGPGAPK KANLINELMM EKKSVQSSLP EWSGAGEFPT AFNLGSTGEQ IYRMQSLSPV CSGLENEQFK SPGNRVSRLS HLRHHYSKKW HRFRFNPKFY SFLSAQEPSH KIGTSLSSLT GSGKRNRIRS SLPWRQNSWK GYSENMRKLR KTHDIPCPDL PWSY

          Target Information

          Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Ca(2+)/calmodulin-dependent protein kinase phosphatase N; calmodulin-dependent protein kinase phosphatase N; CaMKN; CaMKP-N; CaMKP-nucleus; nuclear calmodulin-dependent protein kinase phosphatase; Partner of PIX 1; Partner of PIX-alpha; Partner of PIXA; PP2C eta; PP2C-eta; PP2CE; Protein phosphatase 1E; protein phosphatase 1E (PP2C domain containing); Protein phosphatase 1M; protein phosphatase 1M (PP2C domain containing); protein phosphatase 2C eta; protein phosphatase 2C eta-2; Protein phosphatase 2C isoform eta; protein phosphatase, Mg2+/Mn2+ dependent, 1M; protein phosphatase; POPX1; unnamed protein product

          View more View less

          Gene Aliases: 2810423O19Rik; AW049266; AW610647; B930008A12Rik; C77250; CAMKN; CaMKP-N; CAMKPN; KIAA1072; mKIAA1072; POPX1; PP2C-eta; PP2CE; PP2Ceta; PP2CH; PPM1E; PPM1M

          View more View less

          UniProt ID: (Human) Q8WY54, (Human) Q96MI6, (Mouse) Q80TL0, (Rat) Q80Z30, (Mouse) Q8BU27

          View more View less

          Entrez Gene ID: (Human) 22843, (Human) 132160, (Mouse) 320472, (Rat) 360593, (Rat) 686298, (Mouse) 67905

          View more View less

          Function(s)
          phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein binding hydrolase activity cation binding metal ion binding [pyruvate dehydrogenase (lipoamide)] phosphatase activity manganese ion binding catalytic activity CTD phosphatase activity protein phosphatase
          Process(es)
          negative regulation of protein kinase activity signal transduction peptidyl-threonine dephosphorylation positive regulation of stress fiber assembly cellular response to lipopolysaccharide cellular response to xenobiotic stimulus protein dephosphorylation cellular response to drug metabolic process
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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