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Search Thermo Fisher Scientific
Immunogen sequence: TVIVVFLRDM NKAVNVSEES DWTENSFQGG QEDGGDDKEN HGECKRPWPQ HQCSAPADLG YDGRVDSFTD RTSLSPGSQI NVLE
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 98%.
Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphorylates PRKAA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ca(2+)/calmodulin-dependent protein kinase phosphatase N; CaMKN; CaMKP-N; CaMKP-nucleus; nuclear calmodulin-dependent protein kinase phosphatase; Partner of PIX 1; Partner of PIX-alpha; Partner of PIXA; PP2C-eta; Protein phosphatase 1E; protein phosphatase 1E (PP2C domain containing); Protein phosphatase 1M; protein phosphatase 1M (PP2C domain containing); protein phosphatase 2C eta-2; Protein phosphatase 2C isoform eta; protein phosphatase, Mg2+/Mn2+ dependent, 1E; protein phosphatase, Mg2+/Mn2+ dependent, 1M
Gene Aliases: CAMKN; CaMKP-N; KIAA1072; POPX1; PP2C-eta; PP2CE; PP2Ceta; PP2CH; PPM1E; PPM1M
UniProt ID: (Human) Q8WY54, (Human) Q96MI6
Entrez Gene ID: (Human) 22843, (Human) 132160
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