Product References
The eIF2 kinase GCN2 directs keratinocyte collective cell migration during wound healing via coordination of reactive oxygen species and amino acids.
The Journal of biological chemistry
Miles RR,Amin PH,Diaz MB,Misra J,Aukerman E,Das A,Ghosh N,Guith T,Knierman MD,Roy S,Spandau DF,Wek RC
Mon Nov 01 00:00:00 EDT 2021
UVB-induced eIF2α phosphorylation in keratinocytes depends on decreased ATF4, GADD34 and CReP expression levels.
Life sciences
Bahamondes Lorca VA,Bastidas Mayorga BD,Tong L,Wu S
Wed Dec 01 00:00:00 EST 2021
CReP mediates selective translation initiation at the endoplasmic reticulum.
Science advances
Kastan JP,Dobrikova EY,Bryant JD,Gromeier M
Mon Jun 01 00:00:00 EDT 2020
CReP mediates selective translation initiation at the endoplasmic reticulum.
Science advances
Kastan JP,Dobrikova EY,Bryant JD,Gromeier M
Mon Jun 01 00:00:00 EDT 2020
Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.
Cell
Krzyzosiak A,Sigurdardottir A,Luh L,Carrara M,Das I,Schneider K,Bertolotti A
Thu Aug 23 00:00:00 EDT 2018
Target-Based Discovery of an Inhibitor of the Regulatory Phosphatase PPP1R15B.
Cell
Krzyzosiak A,Sigurdardottir A,Luh L,Carrara M,Das I,Schneider K,Bertolotti A
Thu Aug 23 00:00:00 EDT 2018
Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction.
Hepatology (Baltimore, Md.)
Xu X,Krumm C,So JS,Bare CJ,Holman C,Gromada J,Cohen DE,Lee AH
Sat Dec 01 00:00:00 EST 2018
Preemptive Activation of the Integrated Stress Response Protects Mice From Diet-Induced Obesity and Insulin Resistance by Fibroblast Growth Factor 21 Induction.
Hepatology (Baltimore, Md.)
Xu X,Krumm C,So JS,Bare CJ,Holman C,Gromada J,Cohen DE,Lee AH
Sat Dec 01 00:00:00 EST 2018
AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation.
Molecular & cellular proteomics : MCP
Hülsmann J,Kravic B,Weith M,Gstaiger M,Aebersold R,Collins BC,Meyer H
Sun Jul 01 00:00:00 EDT 2018
AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation.
Molecular & cellular proteomics : MCP
Hülsmann J,Kravic B,Weith M,Gstaiger M,Aebersold R,Collins BC,Meyer H
Sun Jul 01 00:00:00 EDT 2018
Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly.
Cell death & disease
Shelkovnikova TA,Dimasi P,Kukharsky MS,An H,Quintiero A,Schirmer C,Buée L,Galas MC,Buchman VL
Thu May 11 00:00:00 EDT 2017
Chronically stressed or stress-preconditioned neurons fail to maintain stress granule assembly.
Cell death & disease
Shelkovnikova TA,Dimasi P,Kukharsky MS,An H,Quintiero A,Schirmer C,Buée L,Galas MC,Buchman VL
Thu May 11 00:00:00 EDT 2017
An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response.
Proceedings of the National Academy of Sciences of the United States of America
De Gassart A,Bujisic B,Zaffalon L,Decosterd LA,Di Micco A,Frera G,Tallant R,Martinon F
Tue Jan 12 00:00:00 EST 2016
An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response.
Proceedings of the National Academy of Sciences of the United States of America
De Gassart A,Bujisic B,Zaffalon L,Decosterd LA,Di Micco A,Frera G,Tallant R,Martinon F
Tue Jan 12 00:00:00 EST 2016
Nuclear Matrix Protein 4 Is a Novel Regulator of Ribosome Biogenesis and Controls the Unfolded Protein Response via Repression of Gadd34 Expression.
The Journal of biological chemistry
Young SK,Shao Y,Bidwell JP,Wek RC
Fri Jun 24 00:00:00 EDT 2016
Nuclear Matrix Protein 4 Is a Novel Regulator of Ribosome Biogenesis and Controls the Unfolded Protein Response via Repression of Gadd34 Expression.
The Journal of biological chemistry
Young SK,Shao Y,Bidwell JP,Wek RC
Fri Jun 24 00:00:00 EDT 2016
Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
Human molecular genetics
Kernohan KD,Tétreault M,Liwak-Muir U,Geraghty MT,Qin W,Venkateswaran S,Davila J,Holcik M,Majewski J,Richer J,Boycott KM
Sun Nov 15 00:00:00 EST 2015
Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
Human molecular genetics
Kernohan KD,Tétreault M,Liwak-Muir U,Geraghty MT,Qin W,Venkateswaran S,Davila J,Holcik M,Majewski J,Richer J,Boycott KM
Sun Nov 15 00:00:00 EST 2015
Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
Human molecular genetics
Kernohan KD,Tétreault M,Liwak-Muir U,Geraghty MT,Qin W,Venkateswaran S,Davila J,Holcik M,Majewski J,Richer J,Boycott KM
Sun Nov 15 00:00:00 EST 2015
Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
Human molecular genetics
Kernohan KD,Tétreault M,Liwak-Muir U,Geraghty MT,Qin W,Venkateswaran S,Davila J,Holcik M,Majewski J,Richer J,Boycott KM
Sun Nov 15 00:00:00 EST 2015
Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
Human molecular genetics
Kernohan KD,Tétreault M,Liwak-Muir U,Geraghty MT,Qin W,Venkateswaran S,Davila J,Holcik M,Majewski J,Richer J,Boycott KM
Sun Nov 15 00:00:00 EST 2015
Homozygous mutation in the eukaryotic translation initiation factor 2alpha phosphatase gene, PPP1R15B, is associated with severe microcephaly, short stature and intellectual disability.
Human molecular genetics
Kernohan KD,Tétreault M,Liwak-Muir U,Geraghty MT,Qin W,Venkateswaran S,Davila J,Holcik M,Majewski J,Richer J,Boycott KM
Sun Nov 15 00:00:00 EST 2015
IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
Molecular and cellular biology
So JS,Cho S,Min SH,Kimball SR,Lee AH
Sat Aug 01 00:00:00 EDT 2015
IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
Molecular and cellular biology
So JS,Cho S,Min SH,Kimball SR,Lee AH
Sat Aug 01 00:00:00 EDT 2015
IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis.
Molecular and cellular biology
So JS,Cho S,Min SH,Kimball SR,Lee AH
Sat Aug 01 00:00:00 EDT 2015
Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation.
PloS one
Friend K,Brooks HA,Propson NE,Thomson JA,Kimble J
Mon May 30 00:00:00 EDT 2016
Embryonic Stem Cell Growth Factors Regulate eIF2α Phosphorylation.
PloS one
Friend K,Brooks HA,Propson NE,Thomson JA,Kimble J
Mon May 30 00:00:00 EDT 2016
DNA Damage Regulates Translation through β-TRCP Targeting of CReP.
PLoS genetics
Loveless TB,Topacio BR,Vashisht AA,Galaang S,Ulrich KM,Young BD,Wohlschlegel JA,Toczyski DP
Mon Jun 01 00:00:00 EDT 2015
DNA Damage Regulates Translation through β-TRCP Targeting of CReP.
PLoS genetics
Loveless TB,Topacio BR,Vashisht AA,Galaang S,Ulrich KM,Young BD,Wohlschlegel JA,Toczyski DP
Mon Jun 01 00:00:00 EDT 2015
Ribosome Reinitiation Directs Gene-specific Translation and Regulates the Integrated Stress Response.
The Journal of biological chemistry
Young SK,Willy JA,Wu C,Sachs MS,Wek RC
Fri Nov 20 00:00:00 EST 2015
Ribosome Reinitiation Directs Gene-specific Translation and Regulates the Integrated Stress Response.
The Journal of biological chemistry
Young SK,Willy JA,Wu C,Sachs MS,Wek RC
Fri Nov 20 00:00:00 EST 2015
Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.
Nature communications
Wu H,Wei L,Fan F,Ji S,Zhang S,Geng J,Hong L,Fan X,Chen Q,Tian J,Jiang M,Sun X,Jin C,Yin ZY,Liu Q,Zhang J,Qin F,Lin KH,Yu JS,Deng X,Wang HR,Zhao B,Johnson RL,Chen L,Zhou D
Thu Feb 19 00:00:00 EST 2015
Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.
Nature communications
Wu H,Wei L,Fan F,Ji S,Zhang S,Geng J,Hong L,Fan X,Chen Q,Tian J,Jiang M,Sun X,Jin C,Yin ZY,Liu Q,Zhang J,Qin F,Lin KH,Yu JS,Deng X,Wang HR,Zhao B,Johnson RL,Chen L,Zhou D
Thu Feb 19 00:00:00 EST 2015
Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism.
Blood
Hahn CK,Lowrey CH
Thu Jul 25 00:00:00 EDT 2013
Eukaryotic initiation factor 2α phosphorylation mediates fetal hemoglobin induction through a post-transcriptional mechanism.
Blood
Hahn CK,Lowrey CH
Thu Jul 25 00:00:00 EDT 2013
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic.
The Journal of biological chemistry
Kloft N,Neukirch C,von Hoven G,Bobkiewicz W,Weis S,Boller K,Husmann M
Fri Oct 12 00:00:00 EDT 2012
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic.
The Journal of biological chemistry
Kloft N,Neukirch C,von Hoven G,Bobkiewicz W,Weis S,Boller K,Husmann M
Fri Oct 12 00:00:00 EDT 2012
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic.
The Journal of biological chemistry
Kloft N,Neukirch C,von Hoven G,Bobkiewicz W,Weis S,Boller K,Husmann M
Fri Oct 12 00:00:00 EDT 2012
A subunit of eukaryotic translation initiation factor 2α-phosphatase (CreP/PPP1R15B) regulates membrane traffic.
The Journal of biological chemistry
Kloft N,Neukirch C,von Hoven G,Bobkiewicz W,Weis S,Boller K,Husmann M
Fri Oct 12 00:00:00 EDT 2012
