FIGURE: 1 / 2
This antibody is predicted to react with bovine, canine, porcine and rat based on sequence homology.
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene.
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Protein Aliases: MGC131915; PP2A B subunit isoform B'-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A, B subunit, B' alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; PP2A, B subunit, R5 alpha isoform; PP2CB; PR61alpha; protein phosphatase 2 regulatory subunit B', alpha; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; protein phosphatase 2, regulatory subunit B', alpha isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform
Gene Aliases: B56A; PPP2R5A; PR61A
UniProt ID: (Human) Q15172
Entrez Gene ID: (Human) 5525
Molecular Function: protein phosphatase