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Product Details
55148-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Peptide |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.22 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
This antibody is specific to PPP3CB.
Target Information
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcineurin A beta; calcineurin A2; Calcineurin subunit A beta; Calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic subunit; CaN Abeta; CNA beta; PP2BA beta; protein phosphatase 2B, catalytic subunit, beta isoform; protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isoform; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase from PCR fragment H32; protein phosphatase-2Bb; RP11-345K20.1; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Gene Aliases: 1110063J16Rik; CALNA2; CALNB; CNA2; Cnab; CnAbeta; PP2Bbeta; PPP3CB
UniProt ID: (Human) P16298, (Mouse) P48453, (Rat) P20651
Entrez Gene ID: (Human) 5532, (Mouse) 19056, (Rat) 24675
Molecular Function:
protein phosphatase
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
signal transduction
Wnt signaling pathway, calcium modulating pathway
heart development
learning
memory
dephosphorylation
calcium ion regulated exocytosis
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
social behavior
cellular response to drug
positive regulation of insulin secretion involved in cellular response to glucose stimulus
Fc-epsilon receptor signaling pathway
T cell proliferation
T cell activation
T cell homeostasis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of synaptic plasticity
axon extension
regulation of insulin secretion
positive regulation of NFAT protein import into nucleus
response to stress
regulation of gene expression
response to amphetamine
muscle cell cellular homeostasis
protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
drug binding
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
protein dimerization activity
phosphoprotein phosphatase activity
calcium-dependent protein serine/threonine phosphatase activity
hydrolase activity
metal ion binding
protein heterodimerization activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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