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Product Details
PA5-70325
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1.0 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
synthetic peptide directed towards the middle region of rat PPP3CB |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5-1.0 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
PBS with 2% sucrose |
Contains |
0.09% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2689737 |
Product Specific Information
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Target Information
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcineurin subunit A beta; Calmodulin-dependent calcineurin A subunit beta isoform; CAM-PRP catalytic subunit; CaN Abeta; CNA beta; protein phosphatase 3, catalytic subunit, beta isoform; protein phosphatase-2Bb; RP11-345K20.1; Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform
Gene Aliases: Calna2; Ppp3cb
UniProt ID: (Rat) P20651
Entrez Gene ID: (Rat) 24675
Molecular Function:
protein phosphatase
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
response to amphetamine
protein phosphorylation
protein dephosphorylation
heart development
regulation of gene expression
dephosphorylation
calcium ion regulated exocytosis
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
social behavior
cellular response to drug
positive regulation of insulin secretion involved in cellular response to glucose stimulus
T cell homeostasis
positive regulation of transcription from RNA polymerase II promoter
muscle cell cellular homeostasis
regulation of insulin secretion
positive regulation of NFAT protein import into nucleus
protein serine/threonine phosphatase activity
calcium-dependent protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
drug binding
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
protein heterodimerization activity
protein dimerization activity
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