Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
10262-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPP4C Fusion Protein Ag0356 (1-307 aa encoded by BC001416)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MAEISDLDR QIEQLRRCEL IKESEVKALC AKAREILVEE SNVQRVDSPV TVCGDIHGQF YDLKELFRVG GDVPETNYLF MGDFVDRGFY SVETFLLLLA LKVRYPDRIT LIRGNHESRQ ITQVYGFYDE CLRKYGSVTV WRYCTEIFDY LSLSAIIDGK IFCVHGGLSP SIQTLDQIRT IDRKQEVPHD GPMCDLLWSD PEDTTGWGVS PRGAGYLFGS DVVAQFNAAN DIDMICRAHQ LVMEGYKWHF NETVLTVWSA PNYCYRCGNV AAILELDEHL QKDFIIFEAA PQETRGIPSK KPVADYFL (1-307 aa encoded by BC001416)
Target Information
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: P PPX; PP-X; pp4; PP4C; protein phosphatase 4 (formerly X), catalytic subunit; protein phosphatase 4, catalytic subunit; Protein phosphatase X; protein phosphatase X, catalytic subunit; Serine/threonine-protein phosphatase 4 catalytic subunit
Gene Aliases: 1110002D08Rik; AU016079; PP-X; PP4; PP4C; PPH3; PPP4; PPP4C; PPX
UniProt ID: (Human) P60510, (Rat) Q5BJ92, (Mouse) P97470
Entrez Gene ID: (Human) 5531, (Rat) 171366, (Mouse) 56420
Molecular Function:
protein phosphatase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support