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Immunogen sequence: MDVERLQEA LKDFEKRGKK EVCPVLDQFL CHVAKTGETI IPFTIQRLCE LLTDPRRNYT GTDKFLRGVE KNVMVVSCVY PSSEKNNSNS LNRMNGVMFP GNSPSYTERS NINGPGTPRP LNRPKVSLSA PMTTNGLPES TDSKEANLQQ NEEKNHSDSS TSESEVSSVS PLKNKHPDED AVEAEGHEVK RLRFDKEGEV RETASQ (1-205 aa encoded by B C110889)
The protein encoded by this gene is a regulatory subunit of the serine/threonine-protein phosphatase 4 complex. In addition to being required for efficient DNA double strand break repair, this complex plays a role in organization of microtubules at centrosomes and processing of spliceosomal snRNPs. Several transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: MGC131930; protein phosphatase 4, regulatory subunit 2; Serine/threonine-protein phosphatase 4 regulatory subunit 2
Gene Aliases: PP4R2; PPP4R2; SBBI57
UniProt ID: (Human) Q9NY27
Entrez Gene ID: (Human) 151987
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