This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Three transcript variants encoding different isoforms have been described for this gene, with one of the isoforms being inactive.
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Protein Aliases: Lysosomal thioesterase PPT2; palmitoyl-protein hydrolase 2; PPT-2; S-thioesterase G14; VE-statin2
Gene Aliases: C6orf8; G14; PPT-2; PPT2
UniProt ID: (Human) Q9UMR5
Entrez Gene ID: (Human) 9374