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          • Primary Antibodies ›
          • PRAMEF6 Antibodies

          Invitrogen

          PRAMEF6 Polyclonal Antibody

          View all (2) PRAMEF6 antibodies

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          Cite PRAMEF6 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          PRAMEF6 Antibody in Western Blot (WB)
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          PRAMEF6 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          PRAMEF6 Antibody (PA5-112669) in WB

          Western Blot analysis of PRAMEF6 in multiple sample types using a PRAMEF6 polyclonal antibody (Product # PA5-112669) at a dilution of 1:2000. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:50,000. Sample types that were tested include: Hela whole cell lysate, MCF-7 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, 293T whole cell lysate, U87 whole cell lysate, Jurkat whole cell lysate . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PRAMEF6 Antibody in Western Blot (WB)
          PRAMEF6 Polyclonal Antibody

          Product Details

          PA5-112669

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          -

          ELISA (ELISA)

          Assay-dependent
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant Human PRAME family member 6 protein (209-476AA)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          4.12 mg/mL

          Amount

          412 µg

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.03% ProClin 300

          Storage conditions

          -20°C or -80°C if preferred

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2867404

          Target Information

          Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation. The CRL2(PRAMEF6) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: PRAME family member 6

          View more View less

          Gene Aliases: PRAMEF6

          View more View less

          UniProt ID: (Human) Q5VXH4

          View more View less

          Entrez Gene ID: (Human) 440561

          View more View less

          Function(s)
          protein binding, bridging involved in substrate recognition for ubiquitination
          Process(es)
          positive regulation of cell proliferation protein ubiquitination negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of cell differentiation negative regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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