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Proteintech
PRC1 Polyclonal Antibody
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Product Details
10110-2-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRC1 Fusion Protein Ag0163 (13-175 aa encoded by BC005140)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VCLQKALNH LREIWELIGI PEDQRLQRTE VVKKHIKELL DMMIAEEESL KERLIKSISV CQKELNTLCS ELHVEPFQEE GETTILQLEK DLRTQVELMR KQKKERKQEL KLLQEQDQEL CEILCMPHYD IDSASVPSLE ELNQFRQHVT TLRETKASRR EEFV (13-175 aa encoded by BC005140)
Target Information
This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anaphase spindle elongation 1 homolog; MGC1671; MGC3669; PRC1; protein regulating cytokinesis 1; Protein regulator of cytokinesis 1
Gene Aliases: ASE1; D7Ertd348e; PRC1
UniProt ID: (Human) O43663, (Mouse) Q99K43
Entrez Gene ID: (Human) 9055, (Mouse) 233406, (Rat) 308761
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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