This Antibody was verified by Cell Treatment to ensure that the antibody binds to the antigen stated. View Details
PA5-30296 targets PRC1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30296 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 191 of Human PRC1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a protein that is involved in cytokinesis. The encoded protein is at high level during S and G2/M and drop dramatically after cell exit mitosis and enter G1. It is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
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Protein Aliases: anaphase spindle elongation 1 homolog; ASE1; PRC1; protein regulating cytokinesis 1; Protein regulator of cytokinesis 1
Gene Aliases: ASE1; D7Ertd348e; PRC1