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Proteintech
PRCP Polyclonal Antibody
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Product Details
15995-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRCP Fusion Protein Ag8869 (147-496 aa encoded by BC001500)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SEQALADFA ELIKHLKRTI PGAENQPVIA IGGSYGGMLA AWFRMKYPHM VVGALAASAP IWQFEDLVPC GVFMKIVTTD FRKSGPHCSE SIHRSWDAIN RLSNTGSGLQ WLTGALHLCS PLTSQDIQHL KDWISETWVN LAMVDYPYAS NFLQPLPAWP IKVVCQYLKN PNVSDSLLLQ NIFQALNVYY NYSGQVKCLN ISETATSSLG TLGWSYQACT EVVMPFCTNG VDDMFEPHSW NLKELSDDCF QQWGVRPRPS WITTMYGGKN ISSHTNIVFS NGELDPWSGG GVTKDITDTL VAVTISEGAH HLDLRTKNAL DPMSVLLARS LEVRHMKNWI RDFYDSAGKQ H (147-496 aa encoded by BC001500)
Target Information
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Angiotensinase C; Lysosomal carboxypeptidase C; Lysosomal Pro-X carboxypeptidase; PRCP; Proline carboxypeptidase; Prolylcarboxypeptidase; prolylcarboxypeptidase (angiotensinase C)
Gene Aliases: 2510048K03Rik; 2610104A14Rik; AI451719; HUMPCP; PCP; PRCP
UniProt ID: (Human) P42785, (Mouse) Q7TMR0
Entrez Gene ID: (Human) 5547, (Mouse) 72461
regulation of thyroid hormone mediated signaling pathway
plasma kallikrein-kinin cascade
negative regulation of systemic arterial blood pressure
proteolysis
blood coagulation, intrinsic pathway
glucose homeostasis
regulation of blood vessel endothelial cell migration
angiogenesis involved in wound healing
energy homeostasis
regulation of reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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