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Invitrogen
PRDM14 Polyclonal Antibody
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Product Details
PA5-40682
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the middle region of human PRDM14
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: GVTPSLEHPA SLHHAISGLL VPPDSSGSDS LPQTLDKDSL QLPEGLCLMQ
Sequence homology: Cow: 86%; Dog: 86%; Horse: 86%; Human: 100%; Pig: 86%; Rabbit: 100%
Target Information
PRDM14 encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PR domain containing 14; PR domain zinc finger protein 14; PR domain-containing 14; PR domain-containing protein 14
Gene Aliases: PFM11; PRDM14
UniProt ID: (Human) Q9GZV8
Entrez Gene ID: (Human) 63978
negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
cell fate specification
inner cell mass cell fate commitment
transcription, DNA-templated
germ cell development
embryo implantation
fertilization
germ-line stem cell population maintenance
histone H3-R26 methylation
somatic stem cell population maintenance
negative regulation of fibroblast growth factor receptor signaling pathway
regulation of DNA methylation
homeostasis of number of cells within a tissue
inactivation of paternal X chromosome
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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