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Immunoprecipitation analysis of Anti-PRDM5 Recombinant Mouse Monoclonal Antibody (Cat. no. 730106). Immunoprecipitation analysis was performed on HEK293 cells over expressing flag tagged PRDM5 protein. Western blot using anti-flag antibody was performed on the raw lysate (lane 1), and samples immunoprecipitated with Anti-PRDM5 Recombinant Mouse Monoclonal Antibody (lane 2).
|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||2-226 of 630 of PRDM5 Protein.|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunoprecipitation (IP)||0.5 mg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PRDM5, a novel member of PR domain protein family, contains a PR-domain at the –NH2 terminus followed by 16 zinc finger motifs. It is found to have a role in cell differentiation and tumorigenesis. Reports suggest PRDM5 causes G2/M arrest and apoptosis upon infection of tumor cells and has been found to be silenced in breast, ovarian and lung cancers, suggesting a potential clinical significance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
PFM2; PR domain containing 5
BCS2; PFM2; PRDM5