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Proteintech
PRDX1 Polyclonal Antibody
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Product Details
15816-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRDX1 Fusion Protein Ag8602 (1-199 aa encoded by BC007063)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Amount
21 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSGNAKIG HPAPNFKATA VMPDGQFKDI SLSDYKGKYV VFFFYPLDFT FVCPTEIIAF SDRAEEFKKL NCQVIGASVD SHFCHLAWVN TPKKQGGLGP MNIPLVSDPK RTIAQDYGVL KADEGISFRG LFIIDDKGIL RQITVNDLPV GRSVDETLRL VQAFQFTDKH GEVCPAGWKP GSDTIKPDVQ KSKEYFSKQK (1-199 aa encoded by BC007063)
Target Information
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ACR1; Alu co-repressor 1; AOEB166; B166; epididymis secretory sperm binding protein; HBP23; Heme-binding 23 kDa protein; macrophage 23 Kd stress protein; Macrophage 23 kDa stress protein; macrophage 23kDa stress protein; macrophase stress protein 22kDa; macrophase stress protein 23 kd; Natural killer cell-enhancing factor A; natural killer-enhancing factor A; NKEF-A; OSF-3; osteoblast specific factor 3; Osteoblast-specific factor 3; PAG; Peroxiredoxin-1; PRDX1; proliferation associated gene (pag); proliferation-associated gene A; Proliferation-associated gene protein; Prx; Prx 1; thioredoxin dependent peroxide reductase 2; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2; Thioredoxin-dependent peroxiredoxin 1; Trx dependent peroxide reductase 2; unnamed protein product
Gene Aliases: Hbp23; MSP23; NKEF-A; NKEFA; OSF-3; OSF3; PAG; PAGA; PAGB; PRDX1; PrdxI; PRX1; PRXI; TDPX2; TDX2; TPxA
UniProt ID: (Human) Q06830, (Mouse) P35700, (Rat) Q63716
Entrez Gene ID: (Human) 5052, (Mouse) 18477, (Rat) 117254
RNA binding
peroxidase activity
protein binding
thioredoxin peroxidase activity
antioxidant activity
oxidoreductase activity
identical protein binding
cadherin binding
peroxiredoxin activity
thioredoxin-dependent peroxiredoxin activity
heme binding
protein homodimerization activity
poly(A) RNA binding
peroxidase
response to reactive oxygen species
skeletal system development
response to oxidative stress
I-kappaB kinase/NF-kappaB signaling
cell proliferation
removal of superoxide radicals
natural killer cell activation
regulation of stress-activated MAPK cascade
erythrocyte homeostasis
natural killer cell mediated cytotoxicity
hydrogen peroxide catabolic process
leukocyte activation
cell redox homeostasis
fibroblast proliferation
regulation of NIK/NF-kappaB signaling
regulation of NF-kappaB import into nucleus
oxidation-reduction process
retina homeostasis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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