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Invitrogen
PRELP Polyclonal Antibody
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FIGURE: 1 / 3
PRELP Antibody (PA5-78631) in IHC (P)
PRELP Polyclonal Antibody detects PRELP protein at secreted on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. PRELP Polyclonal Antibody (Product # PA5-78631) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-78631
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PRELP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.95 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: mouse heart
Predicted Reactivity: Human (100%), Rat (91%), Rhesus Monkey (99%), Bovine (91%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 55 kDa leucine-rich repeat protein of articular cartilage; PRELP; Prolargin; prolargin proteoglycan; Proline-arginine-rich end leucine-rich repeat protein
Gene Aliases: 7330409J17Rik; MST161; MSTP161; PRELP; SLRR2A
UniProt ID: (Human) P51888, (Mouse) Q9JK53
Entrez Gene ID: (Human) 5549, (Mouse) 116847
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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