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Fabgennix
PREX1 Polyclonal Antibody
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Product Details
PREX-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to aino acid region 815-836 of Human PREX1. Peptide was covalently modified.Sequence:QEEDQADSAFPLLSLGPRLSLC
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000031228; P-Rex1; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; PIP3 dependent Rac exchange factor 1; PREX 1; PREX-1; ptdIns(3,4,5)-dependent Rac exchanger 1; SET domain containing 6
Gene Aliases: G630042G04; KIAA1415; P-REX1; PREX1; RGD1306534; Setd6
UniProt ID: (Human) Q8TCU6, (Mouse) Q69ZK0
Entrez Gene ID: (Human) 57580, (Mouse) 277360, (Rat) 311647
superoxide metabolic process
G-protein coupled receptor signaling pathway
actin filament polymerization
T cell differentiation
neutrophil chemotaxis
regulation of actin filament polymerization
regulation of Rho protein signal transduction
intracellular signal transduction
neutrophil activation
positive regulation of GTPase activity
regulation of dendrite development
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of cell adhesion
reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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