Search

  • Order Status
  • Quick Order

Proteintech

PRMT1 Polyclonal Antibody

11 References
View all (16) PRMT1 antibodies

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Datasheet
Certificates
Protocols
Questions & Answers
Tech Support
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
PRMT1 Polyclonal Antibody

Product Details

11279-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
View 5 publications 5 publications

Immunohistochemistry (IHC)

-
View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200
-

Immunocytochemistry (ICC/IF)

1:20-1:200
View 1 publication 1 publication

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells
-

Immunoprecipitation (IP)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PRMT1 Fusion Protein Ag1790 (1-343 aa encoded by BC019268)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MEVSCGQAE SSEKPNAEDM TSKDYYFDSY AHFGIHEEML KDEVRTLTYR NSMFHNRHLF KDKVVLDVGS GTGILCMFAA KAGARKVIGI ECSSISDYAV KIVKANKLDH VVTIIKGKVE EVELPVEKVD IIISEWMGYC LFYESMLNTV LYARDKWLAP DGLIFPDRAT LYVTAIEDRQ YKDYKIHWWE NVYGFDMSCI KDVAIKEPLV DVVDPKQLVT NACLIKEVDI YTVKVEDLTF TSPFCLQVKR NDYVHALVAY FNIEFTRCHK RTGFSTSPES PYTHWKQTVF YMEDYLTVKT GEEIFGTIGM RPNAKNNRDL DFTIDLDFKG QLCELSCSTD YRMR (1-343 aa encoded by BC019268)

Target Information

PRMT1 is a member of the protein arginine N-methyltransferase (PRMT) family. Arginine methylation is an irreversible post translational modification which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These proteins include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Increased expression of PRMT1 may play a role in various types of cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: arginine N-methyltransferase 1; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2; highly conserved protein 1; Histone-arginine N-methyltransferase PRMT1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; HRMT1L2; Interferon receptor 1-bound protein 4; Protein arginine N-methyltransferase 1; protein arginine N-methyltransferase 1 isoform 10; protein arginine N-methyltransferase 1 isoform 11; protein arginine N-methyltransferase 1 isoform 12; protein arginine N-methyltransferase 1 isoform 13; protein arginine N-methyltransferase 1 isoform 14; protein arginine N-methyltransferase 1 isoform 15; protein arginine N-methyltransferase 1 isoform 16; protein arginine N-methyltransferase 1 isoform 17; protein arginine N-methyltransferase 1 isoform 18; protein arginine N-methyltransferase 1 isoform 19; protein arginine N-methyltransferase 1 isoform 20; protein arginine N-methyltransferase 1 isoform 21; protein arginine N-methyltransferase 1 isoform 22; protein arginine N-methyltransferase 1 isoform 23; protein arginine N-methyltransferase 1 isoform 24; protein arginine N-methyltransferase 1 isoform 25; protein arginine N-methyltransferase 1 isoform 26; protein arginine N-methyltransferase 1 isoform 27; protein arginine N-methyltransferase 1 isoform 28; protein arginine N-methyltransferase 1 isoform 29; protein arginine N-methyltransferase 1 isoform 30; protein arginine N-methyltransferase 1 isoform 31; protein arginine N-methyltransferase 1 isoform 32; protein arginine N-methyltransferase 1 isoform 33; protein arginine N-methyltransferase 1 isoform 34; protein arginine N-methyltransferase 1 isoform 35; protein arginine N-methyltransferase 1 isoform 36; protein arginine N-methyltransferase 1 isoform 37; protein arginine N-methyltransferase 1 isoform 38; protein arginine N-methyltransferase 1 isoform 39; protein arginine N-methyltransferase 1 isoform 4; protein arginine N-methyltransferase 1 isoform 40; protein arginine N-methyltransferase 1 isoform 41; protein arginine N-methyltransferase 1 isoform 42; protein arginine N-methyltransferase 1 isoform 43; protein arginine N-methyltransferase 1 isoform 44; protein arginine N-methyltransferase 1 isoform 45; protein arginine N-methyltransferase 1 isoform 46; protein arginine N-methyltransferase 1 isoform 47; protein arginine N-methyltransferase 1 isoform 48; protein arginine N-methyltransferase 1 isoform 5; protein arginine N-methyltransferase 1 isoform 6; protein arginine N-methyltransferase 1 isoform 7; protein arginine N-methyltransferase 1 isoform 8; protein arginine N-methyltransferase 1 isoform 9; unnamed protein product

View more View less

Gene Aliases: 6720434D09Rik; ANM1; AW214366; HCP1; HMT2; HRMT1L2; IR1B4; Mrmt1; PRMT1

View more View less

UniProt ID: (Human) Q99873, (Mouse) Q9JIF0, (Rat) Q63009

View more View less

Entrez Gene ID: (Human) 3276, (Mouse) 15469, (Rat) 60421

View more View less

Function(s)
RNA binding protein binding methyltransferase activity N-methyltransferase activity protein methyltransferase activity methyl-CpG binding protein-arginine N-methyltransferase activity transferase activity enzyme binding protein-arginine omega-N monomethyltransferase activity protein-arginine omega-N asymmetric methyltransferase activity histone methyltransferase activity identical protein binding histone methyltransferase activity (H4-R3 specific) mitogen-activated protein kinase p38 binding GATOR1 complex binding histone H4 methyltransferase activity S-adenosyl-L-methionine binding rRNA (adenine-N6,N6-)-dimethyltransferase activity protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity C-methyltransferase activity O-methyltransferase activity S-methyltransferase activity RNA methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity histone-arginine N-methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity [cytochrome c]-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity snoRNP binding methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity poly(A) RNA binding P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein modifying enzyme
Process(es)
double-strand break repair via homologous recombination in utero embryonic development chromatin remodeling regulation of transcription, DNA-templated protein methylation cellular response to DNA damage stimulus cell surface receptor signaling pathway positive regulation of cell proliferation RNA splicing negative regulation of translation peptidyl-arginine methylation viral protein processing BMP signaling pathway regulation of BMP signaling pathway negative regulation of BMP signaling pathway neuron projection development cellular response to nutrient levels methylation cellular response to amino acid starvation TORC1 signaling positive regulation of erythrocyte differentiation regulation of megakaryocyte differentiation negative regulation of megakaryocyte differentiation positive regulation of translation negative regulation of translational initiation negative regulation of JNK cascade positive regulation of hemoglobin biosynthetic process cardiac muscle tissue development protein homooligomerization cellular response to methionine protein localization to lysosome membraneless organelle assembly positive regulation of p38MAPK cascade negative regulation of TORC1 signaling positive regulation of TORC1 signaling positive regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination histone methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine peptidyl-arginine N-methylation peptidyl-arginine omega-N-methylation histone H4-R3 methylation liver regeneration
guarantee_icon

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more
help_icon

We're here to help

Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

Contact tech support