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Invitrogen
PRMT3 Polyclonal Antibody
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FIGURE: 1 / 5
PRMT3 Antibody (PA5-115795) in ICC/IF
Immunocytochemistry analysis of PRMT3 in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115795). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115795
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PRMT3(Accession O60678), corresponding to amino acid residues M331-A381.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PRMT3.
Target Information
Type I protein arginine N-methyltransferases (PRMTs), such as PRMT3, catalyze the formation of asymmetric N(G),N(G)-dimethylarginine (ADMA) residues in proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heterogeneous nuclear ribonucleoprotein methyltransferase-like 3; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3; HMT1 hnRNP methyltransferase-like 3; methyltransferase; protein arginine methyltransferase 3; protein arginine N-methyltransferase 3(hnRNP methyltransferase S. cerevisiae)-like 3; unnamed protein product
Gene Aliases: 2010005E20Rik; 2410018A17Rik; HRMT1L3
UniProt ID: (Human) O60678, (Mouse) Q922H1, (Rat) O70467
Entrez Gene ID: (Human) 10196, (Mouse) 71974, (Rat) 89820
protein binding
methyltransferase activity
protein-arginine N-methyltransferase activity
protein-arginine omega-N monomethyltransferase activity
protein-arginine omega-N asymmetric methyltransferase activity
histone methyltransferase activity
histone methyltransferase activity (H4-R3 specific)
modified amino acid binding
S-adenosylmethionine-dependent methyltransferase activity
chromatin remodeling
regulation of transcription, DNA-templated
protein methylation
negative regulation of protein ubiquitination
positive regulation of osteoblast differentiation
positive regulation of gene expression, epigenetic
negative regulation of retinoic acid biosynthetic process
peptidyl-arginine modification
peptidyl-arginine methylation
peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
dendritic spine morphogenesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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