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          • Primary Antibodies ›
          • PRMT4 Antibodies

          Bioss

          PRMT4 Polyclonal Antibody

          View all (17) PRMT4 antibodies

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          Cite PRMT4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (2)
          PRMT4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          PRMT4 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          PRMT4 Antibody (BS-6144R) in WB

          Lane 1: Human 293T Cells; 30ug loaded into the lane; Probed with PRMT4 Polyclonal Antibody, unconjugated (bs-6144R) at 1:500 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PRMT4 Antibody in Western Blot (WB)
          PRMT4 Antibody in Western Blot (WB)
          PRMT4 Polyclonal Antibody

          Product Details

          BS-6144R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          Assay-dependent
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:200
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          KLH conjugated synthetic peptide derived from human PRMT4, amino acids 301-400.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS with 50% glycerol, 1% BSA

          Contains

          0.09% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Coactivator-associated arginine methyltransferase 1; coactivator-associated arginine methyltransferase 1 variant 5; Histone-arginine methyltransferase CARM1; protein arginine methyltransferase; Protein arginine N-methyltransferase 4

          View more View less

          Gene Aliases: CARM1; PRMT4

          View more View less

          UniProt ID: (Human) Q86X55, (Mouse) Q3TYB9, (Rat) Q4AE70

          View more View less

          Entrez Gene ID: (Human) 10498, (Mouse) 59035, (Rat) 363026

          View more View less

          Function(s)
          transcription regulatory region sequence-specific DNA binding transcription coactivator activity protein binding beta-catenin binding methyltransferase activity protein methyltransferase activity histone-arginine N-methyltransferase activity protein-arginine N-methyltransferase activity transferase activity protein-arginine omega-N asymmetric methyltransferase activity histone methyltransferase activity (H3-R17 specific) histone methyltransferase activity histone methyltransferase activity (H3-R2 specific) DNA-binding transcription factor binding rRNA (adenine-N6,N6-)-dimethyltransferase activity protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity RNA methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity ligand-dependent nuclear receptor transcription coactivator activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity protein homodimerization activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity transcription regulatory region DNA binding P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity lysine-acetylated histone binding rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity protein modifying enzyme
          Process(es)
          chromatin organization chromatin remodeling regulation of transcription, DNA-templated apoptotic process positive regulation of cell proliferation methylation regulation of intracellular estrogen receptor signaling pathway positive regulation of fat cell differentiation positive regulation of transcription from RNA polymerase I promoter response to cAMP replication fork reversal positive regulation of epithelial cell apoptotic process negative regulation of dendrite development regulation of growth plate cartilage chondrocyte proliferation transcription, DNA-templated protein methylation pathogenesis chromatin modification histone methylation peptidyl-arginine methylation, to asymmetrical-dimethyl arginine intracellular steroid hormone receptor signaling pathway intracellular estrogen receptor signaling pathway negative regulation of protein binding histone arginine methylation histone H3-R2 methylation histone H3-R17 methylation peptidyl-arginine N-methylation endochondral bone morphogenesis regulation of mRNA binding mRNA processing aging RNA splicing
          It has to be done as per old AB suggested Products section.

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