Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.5-2 µg/mL | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
Assay-Dependent | - |
Immunocytochemistry (ICC/IF) |
2-5 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptides coorresponding to residues 45-69 and 595-608 of human PRMT4. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Protein G |
Storage buffer |
PBS with 0.05% BSA |
Contains |
0.05% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2068426 |
Suggested positive control: Hela whole cell extract, HeLa cell lysate.
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in DNA packaging, transcription regulation, signal transduction, mRNA stability, metabolism of nascent pre-RNA, and transcriptional activation. Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Coactivator-associated arginine methyltransferase 1; Histone-arginine methyltransferase CARM1; Protein arginine N-methyltransferase 4
Gene Aliases: CARM1; PRMT4
UniProt ID: (Human) Q86X55
Entrez Gene ID: (Human) 10498
Molecular Function:
protein modifying enzyme
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