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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8|
|Purification||Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with mouse based on sequence homology.
Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
arginine methyltransferase 8; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 4; HMT1 hnRNP methyltransferase-like 3; HRMT1L3; HRMT1L4; protein arginine N-methyltransferase 4
HRMT1L3; HRMT1L4; PRMT8