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Recommended positive controls: 293T.
Predicted reactivity: Mouse (84%), Bovine (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: p53-induced gene 6 protein; PRODH 1; PRODH 2; proline dehydrogenase (oxidase) 1; Proline dehydrogenase 1, mitochondrial; Proline oxidase; Proline oxidase 2; proline oxidase, mitochondrial; SCZD4; tumor protein p53 inducible protein 6
Gene Aliases: HSPOX2; PIG6; POX; POX2; PRODH; PRODH1; PRODH2; TP53I6
UniProt ID: (Human) O43272
Entrez Gene ID: (Human) 5625
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