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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: p53-induced gene 6 protein; PRODH 1; PRODH 2; proline dehydrogenase (oxidase) 1; proline dehydrogenase (proline oxidase); Proline dehydrogenase 1, mitochondrial; proline dehydrogenase, mitochondrial; Proline oxidase; Proline oxidase 2; proline oxidase, mitochondrial; SCZD4; tumor protein p53 inducible protein 6
Gene Aliases: HSPOX2; PIG6; POX; POX2; Pro-1; Pro1; PRODH; PRODH1; PRODH2; TP53I6; Ym24d07
UniProt ID: (Human) O43272, (Mouse) Q9WU79
Entrez Gene ID: (Human) 5625, (Mouse) 19125, (Rat) 680409
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