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Product Details
PA5-34777
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 127 and 416 of PRP19 (Uniprot ID#Q9UMS4)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2552129
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse stomach.
Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (87%), Pig (99%), Chicken (97%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hPso4; Nuclear matrix protein 200; nuclear matrix protein NMP200 related to splicing factor PRP19; nuclear matrix protein SNEV; Pre-mRNA-processing factor 19; prp19 beta; PRP19/PSO4 homolog; PRP19/PSO4 pre-mRNA processing factor 19 homolog; psoralen 4; RING-type E3 ubiquitin transferase PRP19; Senescence evasion factor
Gene Aliases: AA617263; AL024362; D19Wsu55e; hPSO4; NMP200; PRP19; PRPF19; PSO4; SNEV; UBOX4
UniProt ID: (Human) Q9UMS4, (Mouse) Q99KP6
Entrez Gene ID: (Human) 27339, (Mouse) 28000
protein binding
ligase activity
ubiquitin-ubiquitin ligase activity
identical protein binding
ubiquitin protein ligase activity
ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
RNA processing factor
protein polyubiquitination
spliceosomal tri-snRNP complex assembly
spliceosomal complex assembly
mRNA splicing, via spliceosome
inner cell mass cell proliferation
transcription-coupled nucleotide-excision repair
double-strand break repair via nonhomologous end joining
lipid biosynthetic process
proteasomal protein catabolic process
cellular protein localization
negative regulation of neuron differentiation
positive regulation of mRNA splicing, via spliceosome
positive regulation of astrocyte differentiation
protein K63-linked ubiquitination
signal transduction involved in DNA damage checkpoint
generation of catalytic spliceosome for first transesterification step
DNA repair
mRNA processing
cellular response to DNA damage stimulus
RNA splicing
protein ubiquitination
positive regulation of neuron differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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