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Agrisera
PRP40B/pre-mRNA-processing protein 40B Polyclonal Antibody
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FIGURE: 1 / 1
PRP40B/pre-mRNA-processing protein 40B Antibody (AS14-2785) in WB
Total protein from rosette leaves, 30 µg of Arabidopsis thaliana whole leaf extract (prp 40 ab) (1), 30 µg of Arabidopsis thaliana whole leaf extract (wild-type) (2), extracted with buffer (100 m M Tris, 10% glycerol, 5 m M EDTA, 5 m M EGTA, 0.15 M Na Cl, 0.75% Triton X 100,0.05% SDS, 1 m M DTT) and denatured with 0.06 M Tris-HCl, 5% glycerol, 2% SDS, 4% β-mercaptoethanol, 0.25% bromophenol blue at 95 C for... View More
Product Details
AS14-2785
Product Specifications
Species Reactivity
Plant
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Arabidopsis thaliana PRP40b.
Conjugate
Form
Lyophilized
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
Target Information
PRPF40B encodes an intracellular, predominantly nuclear protein that localizes to nucleoplasm/nuclear bodies (with additional cytosolic signal) and is structurally characterized by N-terminal WW protein-interaction module(s) together with multiple FF domains, consistent with an adaptor/scaffold architecture in RNA-processing pathways. Alternative splicing generates multiple transcript variants encoding distinct isoforms. Based on homology to the yeast U1 snRNP factor Prp40 and curated functional annotations, PRPF40B is implicated in pre-mRNA processing and mRNA splicing, likely contributing to early spliceosome/U1 snRNP-associated protein-protein interactions via its WW and FF domains. Reported interaction data indicate PRPF40B can bind Huntingtin and MeCP2, supporting a role as a multi-partner interaction hub that may link spliceosomal functions with other nuclear protein networks.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: At5g03340; AtPRP40B; HYPC
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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