Immunogen sequence: LDLEEAGDMV AAQADENVGE AGRSLLESPG LTSGSDTPQQ DNDQLNSEEK KKRKQRRNR
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Homeobox protein PHOX1; paired mesoderm homeo box 1; paired mesoderm homeobox 1; paired mesoderm homeobox 1 isoform pmx-1b; Paired mesoderm homeobox protein 1; paired related homeobox 1; Paired-related homeobox protein 1; PHOX1; PMX1; PRRX1; PRX-1; PRX1
Gene Aliases: AGOTC; PHOX1; PMX1; PRRX1; PRX-1; PRX1
UniProt ID: (Human) P54821
Entrez Gene ID: (Human) 5396