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          • Primary Antibodies ›
          • PRX Antibodies

          Invitrogen

          PRX Polyclonal Antibody

          Advanced Verification
          View all (4) PRX antibodies

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          Cite PRX Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (5)
          • Advanced Verification (2)
          PRX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PRX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          PRX Antibody (PA5-51646) in IHC (P)

          Immunohistochemical analysis of PRX in human lung using PRX Polyclonal Antibody (Product # PA5-51646) shows strong membranous positivity in pneumocytes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PRX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PRX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PRX Antibody in Immunohistochemistry (IHC)
          PRX Antibody in Immunohistochemistry (IHC)
          PRX Antibody in Immunohistochemistry (IHC)
          PRX Antibody
          PRX Antibody
          PRX Polyclonal Antibody

          Product Details

          PA5-51646

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human PRX. Recombinant protein control fragment (Product #RP-100995).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2646041

          Product Specific Information

          Immunogen sequence: MKVPDMKLPE IKLPKVPEMA VPDVHLPEVQ LPKVSEIRLP EMQVPKVPDV HLPKAPEVKL PRAPEVQLKA TKAEQAEGME FGFKMPKMTM PKLGRAESPS RGKPGEAGAE VSGKLVTLPC LQPEVDGEAH VGVPSLTLPS VELDL

          Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 68%.

          Target Information

          Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: PDZ domain protein; Periaxin

          View more View less

          Gene Aliases: CMT4F; KIAA1620; PRX

          View more View less

          UniProt ID: (Human) Q9BXM0

          View more View less

          Entrez Gene ID: (Human) 57716

          View more View less

          Function(s)
          protein binding
          Process(es)
          axon ensheathment peripheral nervous system myelin maintenance regulation of RNA splicing
          It has to be done as per old AB suggested Products section.

          Disclaimer

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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