Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Positive test controls include: LNCaP. The target is usually found in the following locations: Secreted.
Immunogen sequence: ECEKHSQPWQ VLVASRGRAV CGGVLVHPQW VLTAAHCIRN KSVILLGRHS LFHPEDTGQV FQVSHSFPHP LYDMSLLKNR FLRPGDDSSH DLMLLRLSEP AELTDAVKVM DLPTQEPALG TTCYASGWGS IEPEEFLTPK KLQCVDLHVI SNDVCAQVHP QKVTKFMLCA GRWTGGKSTC SGDSGGPLVC NGVLQGITSW GSEPCALPER PSLYTKVVHY RKWIKDTIVA NP
PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 7S nerve growth factor gamma chain; 7S nerve growth factor gamma subunit; Antigen; Gamma-NGF; Gamma-seminoprotein; Glandular kallikrein K3; Kallikrein 1-related peptidase b3; Kallikrein 3; Kallikrein-3; Kallikrein-3 (KLK3); kallikrein-related peptidase 3; KLK-3; mGK-3; nerve growth factor, gamma; P-30 antigen; prostate specific antigen; prostate-specific (APS); Prostate-specific antigen; PSA; Semenogelase; Seminin; Tissue kallikrein-3
Gene Aliases: APS; hK3; Klk-3; Klk1b3; KLK2A1; KLK3; mGk-3; Ngfg; PSA
UniProt ID: (Human) P07288, (Mouse) P00756
Entrez Gene ID: (Human) 354, (Mouse) 18050
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support