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Invitrogen
PSCA Polyclonal Antibody
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Product Details
PA5-65080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human PSCA. Recombinant protein control fragment (Product #RP-105840).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LLCYSCKAQVS NEDCLQVENC TQLGEQCWTA RIRAVGLLTV ISKGCSLNCV DDSQDYYVGK KNITCCDTDL CNASGAHALQ PAAAILALLP ALGLLLW
Highest antigen sequence identity to the following orthologs - mouse 59%, rat 60%.
Target Information
PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in approximately40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: caldesmon; CDM; GPI-anchored cell surface protein; H-CAD; HCAD; L-CAD; LCAD; NAG22; Prostate stem cell antigen; UNQ206
Gene Aliases: lncPSCA; PRO232; PSCA; UNQ206/PRO232
UniProt ID: (Human) O43653
Entrez Gene ID: (Human) 8000
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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