Invitrogen

PSD4 Polyclonal Antibody

Advanced Verification

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details

View all (4) PSD4 antibodies

Datasheet

Questions & Answers

Datasheet

Questions & Answers

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PSD4 Antibody in Immunohistochemistry (IHC) — Immunohistochemical staining of PSD4 in human skeletal muscle using PSD4 Polyclonal Antibody (Product # PA5-57029) shows low expression as expected.

PSD4 Antibody in Relative expression — Relative expression in different tissues in IHC: Detection of differential expression levels of PSD4 demonstrates antibody specificity. Immunohistochemical analysis of PSD4 using anti-PSD4 Polyclonal Antibody (Product # PA5-57029), shows significant staining of PSD4 in human tonsil and shows minimal or weak staining in human skeletal muscle tissues. The relative expression levels of PSD4 within each tissue is shown using RNA-Seq. {RE}

Product Details

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:50-1:200

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PSD4

Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2646045

Product Specific Information

Immunogen sequence: EESMFFSNPL FLASPCSENS ASGECFSWGA SDSHAGVRTG PESPATLEPP LPEDTVLWEL ESEPDLGDGA AISGHCTPPF PVPIYKPHSI

Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 55%.

Target Information

Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ADP-ribosylation factor guanine nucleotide-exchange factor 6; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; Exchange factor for ARF6 B; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; SEC7 homolog; Telomeric of interleukin-1 cluster protein

Gene Aliases: EFA6B; PSD4; TIC

UniProt ID: (Human) Q8NDX1

Entrez Gene ID: (Human) 23550

Molecular Function: G-protein modulator enzyme modulator guanyl-nucleotide exchange factor