This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: PGSPVNSHLP GSPKQNRSTS TQVVFWAGIL QAQMCVLDLE EELEKTEGLK AGLKCCLPTP PVDLPGDTGL HSSPPENEDS GEDSSEPEGE GQAWLREGTP DSSPQW
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 67%.
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosylation factor guanine nucleotide-exchange factor 6; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; Exchange factor for ARF6 B; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; SEC7 homolog; Telomeric of interleukin-1 cluster protein
Gene Aliases: EFA6B; PSD4; TIC
UniProt ID: (Human) Q8NDX1
Entrez Gene ID: (Human) 23550