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Proteintech
PSMA6 Polyclonal Antibody
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Product Details
11573-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mollusc
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSMA6 Fusion Protein Ag2154 (1-246 aa encoded by BC023659)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSRGSSAGF DRHITIFSPE GRLYQVEYAF KAINQGGLTS VAVRGKDCAV IVTQKKVPDK LLDSSTVTHL FKITENIGCV MTGMTADSRS QVQRARYEAA NWKYKYGYEI PVDMLCKRIA DISQVYTQNA EMRPLGCCMI LIGIDEEQGP QVYKCDPAGY YCGFKATAAG VKQTESTSFL EKKVKKKFDW TFEQTVETAI TCLSTVLSID FKPSEIEVGV VTVENPKFRI LTEAEIDAHL VALAERD (1-246 aa encoded by BC023659)
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 27 kDa prosomal protein; alpha-1; Macropain iota chain; macropain subunit iota; MGC22756; MGC2333; MGC23846; Multicatalytic endopeptidase complex iota chain; PROS 27; PROS-27; prosomal P27K protein; proteasome (prosome, macropain) subunit, alpha type, 6; proteasome alpha 6 subunit; Proteasome iota chain; proteasome subunit alpha 6; Proteasome subunit alpha type-6; Proteasome subunit alpha-1; proteasome subunit alpha1; proteasome subunit iota; PSA6; PSMA 6; PSMA6; testicular secretory protein Li 44; unnamed protein product
Gene Aliases: IOTA; p27K; PROS27; PSMA6
UniProt ID: (Human) P60900, (Mouse) Q9QUM9, (Rat) P60901
Entrez Gene ID: (Human) 5687, (Mouse) 26443, (Rat) 29673
ubiquitin-dependent protein catabolic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of inflammatory response
proteolysis involved in cellular protein catabolic process
proteolysis
skeletal muscle tissue development
proteasomal ubiquitin-independent protein catabolic process
positive regulation of NF-kappaB transcription factor activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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