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Proteintech
PSMB1 Polyclonal Antibody
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FIGURE: 1 / 8
PSMB1 Antibody (11749-1-AP) in ICC/IF
Immunofluorescent analysis of (-20°C Ethanol) fixed U2OS cells using (Product # 11749-1-AP) (PSMB1 antibody), at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Red stain with CL594-Phalloidin. Blue stain with DAPI.
Product Details
11749-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSMB1 Fusion Protein Ag2345 (1-241 aa encoded by BC020807)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MLSSTAMYS APGRDLGMEP HRAAGPLQLR FSPYVFNGGT ILAIAGEDFA IVASDTRLSE GFSIHTRDSP KCYKLTDKTV IGCSGFHGDC LTLTKIIEAR LKMYKHSNNK AMTTGAIAAM LSTILYSRRF FPYYVYNIIG GLDEEGKGAV YSFDPVGSYQ RDSFKAGGSA SAMLQPLLDN QVGFKNMQNV EHVPLSLDRA MRLVKDVFIS AAERDVYTGD ALRICIVTKE GIREETVSLR KD (1-241 aa encoded by BC020807)
Target Information
PSMB1 is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: beta-6; component C5 of proteasome; Macropain subunit C5; Multicatalytic endopeptidase complex subunit C5; proteasome (prosome, macropain) subunit, beta type, 1; proteasome beta 1 subunit; proteasome beta-subunit C5; Proteasome component C5; Proteasome gamma chain; Proteasome subunit beta type-1; Proteasome subunit beta-6; proteasome subunit C5; proteasome subunit HC5; proteasome subunit RC5; testicular secretory protein Li 45
Gene Aliases: AA409053; C81484; HC5; Lmpc5; PMSB1; PSC5; PSMB1
UniProt ID: (Human) P20618, (Mouse) O09061, (Rat) P18421
Entrez Gene ID: (Human) 5689, (Mouse) 19170, (Rat) 94198
MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
viral process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
proteolysis
proteasomal ubiquitin-independent protein catabolic process
proteolysis involved in cellular protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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