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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (NRFQIATVTE) corresponding to the internal amino acids of PSMB4|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.1-0.3 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with bovine, canine and rabbit based on sequence homology.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
26 kDa prosomal protein; hsBPROS26; HsN3; low molecular mass protein 3; macropain beta chain; multicatalytic endopeptidase complex beta chain; PROS26; proteasome (prosome, macropain) subunit, beta type, 4; proteasome beta 4 subunit; proteasome beta chain; proteasome chain 3; proteasome subunit beta type-4; proteasome subunit HsN3; proteasome subunit, beta type, 4; PSMB4; RN3; testis tissue sperm-binding protein Li 79P
HN3; HsN3; Lmp3; PROS-26; Pros-27; PROS26; PSMB4