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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.3-1 µg/mL | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Rat |
Host/Isotype |
Goat / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide sequence (RNISYKYRED) corresponding to the internal amino acids of PSMB9 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.5 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
TBS, pH 7.3, with 0.5% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_10978133 |
This antibody is predicted to react with bovine, canine, mouse, porcine and rabbit based on sequence homology.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: large multifunctional peptidase 2; large multifunctional protease 2; low molecular mass polypeptide 2; Low molecular mass protein 2; Macropain chain 7; MGC70470; Multicatalytic endopeptidase complex chain 7; proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2); proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); proteasome catalytic subunit 1i; Proteasome chain 7; proteasome subunit beta 6i; Proteasome subunit beta type-9; Proteasome subunit beta-1i; proteasome-related gene 2; proteosome (prosome, macropain) subunit, beta type 9; Really interesting new gene 12 protein; RING12 protein
Gene Aliases: beta1i; LMP2; PSMB6i; PSMB9; RING12
UniProt ID: (Human) P28065, (Rat) P28077
Entrez Gene ID: (Human) 5698, (Rat) 24967
Molecular Function:
protease
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