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Invitrogen
PSMB9 Polyclonal Antibody
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Product Details
PA5-19384
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (RNISYKYRED) corresponding to the internal amino acids of PSMB9 (aa 104-113).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, canine, mouse, porcine and rabbit based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: large multifunctional peptidase 2; large multifunctional protease 2; low molecular mass polypeptide 2; Low molecular mass protein 2; Macropain chain 7; MGC70470; Multicatalytic endopeptidase complex chain 7; proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2); proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2); proteasome catalytic subunit 1i; Proteasome chain 7; proteasome subunit beta 6i; Proteasome subunit beta type-9; Proteasome subunit beta-1i; proteasome-related gene 2; proteosome (prosome, macropain) subunit, beta type 9; Really interesting new gene 12 protein; RING12 protein
Gene Aliases: beta1i; LMP2; PSMB6i; PSMB9; RING12
UniProt ID: (Human) P28065, (Rat) P28077
Entrez Gene ID: (Human) 5698, (Rat) 24967
MAPK cascade
protein polyubiquitination
liver development
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
regulation of cellular amino acid metabolic process
muscle atrophy
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
response to drug
proteasome-mediated ubiquitin-dependent protein catabolic process
response to alkaloid
regulation of mRNA stability
spleen development
thymus development
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
cellular response to electrical stimulus
cellular response to interleukin-1
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
cellular response to virus
response to benzene
regulation of cysteine-type endopeptidase activity
immune system process
antigen processing and presentation
proteolysis involved in cellular protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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