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Product Details
15839-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSMC6 Fusion Protein Ag8589 (1-389 aa encoded by BC005390)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MADPRDKAL QDYRKKLLEH KEIDGRLKEL REQLKELTKQ YEKSENDLKA LQSVGQIVGE VLKQLTEEKF IVKATNGPRY VVGCRRQLDK SKLKPGTRVA LDMTTLTIMR YLPREVDPLV YNMSHEDPGN VSYSEIGGLS EQIRELREVI ELPLTNPELF QRVGIIPPKG CLLYGPPGTG KTLLARAVAS QLDCNFLKVV SSSIVDKYIG ESARLIREMF NYARDHQPCI IFMDEIDAIG GRRFSEGTSA DREIQRTLME LLNQMDGFDT LHRVKMIMAT NRPDTLDPAL LRPGRLDRKI HIDLPNEQAR LDILKIHAGP ITKHGEIDYE AIVKLSDGFN GADLRNVCTE AGMFAIRADH DFVVQEDFMK AVRKVADSKK LESKLDYKPV (1-389 aa encoded by BC005390)
Target Information
PSMC6 (proteasome (prosome, macropain) 26S subunit, ATPase 6), also known as P44, p42, SUG2, S10B or CADP44, is a regulatory component of the 26S proteasome. More specifically, PSMC6 is one of the six ATPase subunits of the 19S regulator base. It contains a leucine zipper motif and an AAA (ATPase associated with diverse cellular activities) domain and belongs to the AAA ATPase family of chaperone-like ATPases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 26S protease regulatory subunit 10B; 26S protease regulatory subunit S10B; 26S proteasome AAA-ATPase subunit RPT4; 26S proteasome regulatory subunit 10B; conserved ATPase domain protein 44; epididymis secretory protein Li 73; proteasome (prosome, macropain) 26S subunit, ATPase, 6; proteasome (prosome, macropain) 26S subunit, ATPase, 6-like; Proteasome 26S subunit ATPase 6; Proteasome subunit p42
Gene Aliases: 2300001E01Rik; AI451058; CADP44; HEL-S-73; p42; P44; PSMC6; SUG2
UniProt ID: (Human) P62333, (Mouse) P62334
Entrez Gene ID: (Human) 5706, (Mouse) 67089, (Rat) 289990
Molecular Function:
protease
MAPK cascade
protein polyubiquitination
stimulatory C-type lectin receptor signaling pathway
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
ubiquitin-dependent protein catabolic process
regulation of cellular amino acid metabolic process
ER-associated ubiquitin-dependent protein catabolic process
anaphase-promoting complex-dependent catabolic process
tumor necrosis factor-mediated signaling pathway
NIK/NF-kappaB signaling
Fc-epsilon receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of mRNA stability
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
T cell receptor signaling pathway
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of proteasomal protein catabolic process
protein catabolic process
positive regulation of inclusion body assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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