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Bethyl Laboratories
PSMD3 Polyclonal Antibody
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FIGURE: 1 / 2
PSMD3 Antibody (A303-826A) in IHC (P)
Detection of human PSMD3 by immunohistochemistry. Samples: FFPE sections of human lung cancer (left) and prostate carcinoma (right). Antibody: Affinity purified rabbit anti-PSMD3 (Product # A303-826A) (Lot 1) used at a dilution of 1:1,000 (1 µg/mL). Detection: DAB. Counterstain: hematoxylin (blue).
Product Details
A303-826A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of Human Proteasome (prosome, macropain) 26S subunit, non-ATPase, 3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Bovine
Target Information
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 26S proteasome non-ATPase regulatory subunit 3; 26S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; Proteasome subunit p58; PSMD3; tissue specific transplantation antigen 2; tissue specific transplantation antigen P91A; Transplantation antigen P91A; Tum-P91A antigen; unnamed protein product
Gene Aliases: AI255837; AntP91a; D11Bwg1349e; P58; P91a; Psd3; PSMD3; RPN3; S3; TSTA2; Tstap91a
UniProt ID: (Human) O43242, (Mouse) P14685
Entrez Gene ID: (Human) 5709, (Mouse) 22123
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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