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Immunogen sequence: MPLENLEEE GLPKNPDLRI AQLRFLLSLP EHRGDAAVRD ELMAAVRDNN MAPYYEALCK SLDWQIDVDL LNKMKKANED ELKRLDEELE DAEKNLGESE IRDAMMAKAE YLCRIGDKEG ALTAFRKTYD KTVALGHRLD IVFYLLRIGL FYMDNDLITR NTEKAKSLIE EGGDWDRRNR LKVYQGLYCV AIRDFKQAAE LFLDTVSTFT SYELMDYKTF VTYTVYVSMI ALERPDLREK VIKGAEILEV LHSLPAVRQY LFSLYECRYS VFFQSLAVVE QEMKKDWLFA PHYRYYVREM RIHAYSQLLE SYRSLTLGYM AEAFGVGVEF IDQELSRFIA AGRLHCKIDK VNEIVETNRP D (1-360 aa encoded by BC012369)
This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; p42A; Phosphonoformate immuno-associated protein 4; proteasome (prosome, macropain) 26S subunit, non-ATPase, 6; Proteasome regulatory particle subunit p44S10; proteasome, 26S, non-ATPase regulatory subunit 6
Gene Aliases: 2400006A19Rik; KIAA0107; p42A; P44s10; PFAAP4; PSMD6; Rpn7; S10; SGA-113M
UniProt ID: (Human) Q15008, (Mouse) Q99JI4
Entrez Gene ID: (Human) 9861, (Rat) 289924, (Mouse) 66413
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