This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants.
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Protein Aliases: 26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; p42A; Phosphonoformate immuno-associated protein 4; proteasome (prosome, macropain) 26S subunit, non-ATPase, 6; Proteasome regulatory particle subunit p44S10; proteasome, 26S, non-ATPase regulatory subunit 6
Gene Aliases: 2400006A19Rik; KIAA0107; p42A; P44s10; PFAAP4; PSMD6; Rpn7; S10; SGA-113M